
What Is Motilium and How Does It Work
Motilium, also known as domperidone, is a medication designed to address problems related to the movement of the stomach and intestines. It helps people who experience symptoms like nausea, vomiting, bloating, or stomach discomfort often related to slow gastric emptying. By enhancing the action of the natural chemical dopamine in the gut, Motilium helps speed up the passage of food through the digestive system, making it an effective remedy for those struggling with gastrointestinal symptoms.
Unlike many other medications that act on the brain, Motilium primarily affects dopamine receptors found in the digestive tract. This targeted approach means it can relieve symptoms without causing significant drowsiness or sedation. Because of its unique mechanism, Motilium has become a valuable option for patients who need faster relief from uncomfortable gastric complaints.
Feature | Description |
---|---|
Active Ingredient | Domperidone |
Main Use | Relieves nausea, vomiting, and gastric discomfort |
How It Works | Blocks dopamine receptors in GI tract to increase bowel movements |
Common Dosage Forms and Strengths Explained

Motilium is available in several easily accessible forms to suit individual needs. Most commonly, it comes as tablets containing 10 mg of domperidone, but there are also orodispersible tablets and an oral suspension format, making it convenient for those who may have trouble swallowing pills.
The oral suspension is particularly useful for children, as it allows for more precise dose adjustments based on body weight. No matter the format, each is designed to deliver consistent relief while ensuring accurate dosing for all age groups.
Recommended Dosages for Adults and Children
When it comes to finding relief with motilium, understanding how much to take and when is critical for safe and effective results. In adults, the medication is often prescribed at a standard dose of 10 mg, taken up to three times daily before meals. This schedule helps ensure optimal absorption and effectiveness while minimizing the risk of uncomfortable side effects. However, adjustments may be necessary based on individual health needs and a doctor's recommendations.
For children, dosing is generally determined by body weight, and a healthcare professional should always calculate the precise amount. Liquid formulations are frequently chosen for younger patients to allow for more accurate dosing. Regardless of age, it’s vital to follow your provider’s instructions carefully and not exceed the recommended duration of treatment with motilium, as longer use may increase safety concerns.
Key Precautions before Taking Motilium

Before starting motilium, it’s important to review your medical history with a healthcare professional. People with certain heart conditions—such as arrhythmias or prolonged QT interval—should avoid motilium, as it may increase the risk of serious cardiac side effects. Additionally, those with liver problems need special consideration, since the medication is metabolized in the liver and its use could worsen existing issues.
Women who are pregnant or breastfeeding should use motilium only if advised by a doctor, as its safety profile in these situations has not been fully established. Likewise, anyone with known allergies to domperidone or any other ingredient in motilium must inform their physician immediately.
Pay close attention to any signs of gastrointestinal bleeding or blockage—such as persistent vomiting or severe abdominal pain—because motilium may not be suitable in those circumstances.
Potential Side Effects to Watch Out for
When starting motilium, most people tolerate it well, but some may notice mild digestive disturbances like stomach cramps or diarrhea. While these symptoms are typically short-lived, it’s important to pay attention if you develop unexpected or severe reactions. For instance, rarely, individuals experience headaches, dizziness, or even heart rhythm changes, which require immediate medical advice.
Older adults or those with heart conditions should be particularly cautious, as motilium can occasionally affect heart electrical activity. Promptly report any palpitations, fainting, or chest pain.
Common Side Effects | Rare But Serious Effects |
---|---|
Nausea, dry mouth, abdominal cramps | Irregular heartbeat, fainting, chest pain |
Important Drug Interactions and Safety Warnings
Motilium’s effectiveness can come at a cost if mixed with the wrong medications. Combining it with certain antibiotics or antifungals, for instance, may dramatically raise the risk of heart rhythm problems. People on medications that alter liver enzymes—such as some antidepressants and antifungals—should be especially cautious, as drug levels could spike dangerously. Furthermore, Motilium is generally unsuitable for those with existing cardiac conditions, or who are already taking other drugs known to prolong the QT interval. Always consult a healthcare provider to thoroughly review all prescription, over-the-counter, and herbal medications before starting Motilium. NCBI: Domperidone safety European Medicines Agency: Motilium assessment